“It’s ideal to have more than one or two companies being the sole providers of vaccines,” Dr. Even though Pfizer-BioNTech and Moderna mRNA vaccines are safe and highly effective, “we’ve heard a lot of people say the reason they've chosen not to get an mRNA vaccine is because the mRNA technology is relatively new and it hasn't been tried on a wide scale before.” One is that this is an additional vaccine choice that may be acceptable to some of the more than 30% of Americans who are not fully vaccinated, he explains. Perry Wilson, MD, a Yale Medicine nephrologist and epidemiologist. “It’s good news for many reasons,” says F. Novavax says it expects to have an updated shot in 2023 but says its booster does provide protection against several strains, including BA.5. While the mRNA bivalent boosters from Pfizer and Moderna target both the original strain of the coronavirus and Omicron BA.4 and BA.5 subvariants, the Novavax booster only targets the original SARS-CoV-2 virus. Then, in October, the FDA authorized a booster for adults only, although it may not prevent infection by the most recent variants. It’s important to note that, for both age groups, the data on the vaccine’s efficacy was gathered before Omicron became the predominant variant, so its efficacy against Omicron and its subvariants is unknown. In August, authorization for the vaccine was expanded to include adolescents ages 12 to 17, based on data from Novavax’s ongoing pediatric trial. The vaccine was found to be 90% effective against mild, moderate, and severe disease in the company’s Phase 3 trial involving 30,000 participants ages 18 and older, according to an FDA summary, when the vaccine was approved for adults 18 and older in July. It’s unique among the available coronavirus vaccines in this country in that it uses a traditional virus-blocking technology (one that’s been used against other diseases). for the prevention of COVID-19 and another tool in an expanding armamentarium. The Novavax vaccine is the fourth vaccine authorized by the Food and Drug Administration (FDA) in the U.S. Because information about COVID-19 changes rapidly, we encourage you to visit the websites of the Centers for Disease Control & Prevention (CDC), World Health Organization (WHO), and your state and local government for the latest information. Note: Information in this article was accurate at the time of original publication.
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